Ropinirole suppresses LPS-induced periodontal inflammation by inhibiting the NAT10 in an ac4C-dependent manner

Abstract Background Periodontitis is a chronic osteolytic inflammatory disease, where anti-inflammatory intervention is critical for restricting periodontal damage and regenerating alveolar bone. Ropinirole, a dopamine D2 receptor agonist, has previously shown therapeutic potential for periodontitis...

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Bibliographic Details

Published in:	BMC Oral Health
Main Authors:	Haiqing Liao, Huabing Ma, Hongying Meng, Na Kang, Lufei Wang
Format:	Article
Language:	English
Published:	BMC 2024-04-01
Subjects:	Periodontitis Human gingival fibroblasts NAT10 ac4C KLF6
Online Access:	https://doi.org/10.1186/s12903-024-04250-5