Adaptive Clinical Trials and Sample Size Determination in the Presence of Measurement Error and Heterogeneity

Adaptive clinical trials offer a flexible approach for refining sample sizes during ongoing research to enhance their efficiency. This study delves into improving sample size recalculation through resampling techniques, employing measurement error and mixed distribution models. The research employs...

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Bibliographic Details

Published in:	Stats
Main Authors:	Hassan Farooq, Sajid Ali, Ismail Shah, Ibrahim A. Nafisah, Mohammed M. A. Almazah
Format:	Article
Language:	English
Published:	MDPI AG 2025-04-01
Subjects:	adaptive clinical trials group sequential design measurement error in trials promising zone observed conditional power sample size determination
Online Access:	https://www.mdpi.com/2571-905X/8/2/31