Case report: Active clinical manifestation of endocardial fibroelastosis in adolescence in a patient with mitral and aortic obstruction–histologic presence of endothelial-to-mesenchymal transformation

This is the first description of active clinical manifestation of endocardial fibroelastosis (EFE) and remodeling of the endocardium via endothelial-to-mesenchymal transformation (EndMT) in an adolescent with Shone’s variant hypoplastic left heart complex (HLHC) and a genetic heterozygous ABL1 varia...

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Bibliographic Details

Published in:	Frontiers in Cardiovascular Medicine
Main Authors:	Daniel Diaz-Gil, Chrystalle Katte Carreon, Natalia Silva-Gomez, Alan E. Benheim, Sitaram M. Emani, Pedro J. del Nido, Gerald R. Marx, Ingeborg Friehs
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Subjects:	endocardial fibroelastosis hypoplastic left heart complex endothelial-to-mesenchymal transformation ABL1 flow disturbance
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2022.1041039/full