Thrombospondin 1 in Metabolic Diseases

The thrombospondin family comprises of five multifunctional glycoproteins, whose best-studied member is thrombospondin 1 (TSP1). This matricellular protein is a potent antiangiogenic agent that inhibits endothelial migration and proliferation, and induces endothelial apoptosis. Studies have demonstr...

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Bibliographic Details
Published in:Frontiers in Endocrinology
Main Authors: Linda S. Gutierrez, Jovita Gutierrez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.638536/full