Comparative effects of glycopyrrolate vs. atropine combined with neostigmine on heart rate dynamics and safety outcomes in pediatric patients: a prospective randomized controlled trial

Abstract Background Neostigmine is a widely used muscle relaxant antagonist that requires combination with anticholinergic agents like atropine to mitigate its muscarinic effects. Glycopyrrolate exerts less influence on cardiac conduction than atropine, making it a preferable option. However, clinic...

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Bibliographic Details

Published in:	BMC Pediatrics
Main Authors:	Tianxiao Zou, Xueting Yang, Lulu Ren, Sisi Wei, Guoqing Wang, Rong Wei, Shenghua Yu
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Glycopyrrolate Heart rate Atropine Neostigmine Pediatric Anesthesia
Online Access:	https://doi.org/10.1186/s12887-025-06092-8