Menin inhibitors from monotherapies to combination therapies: clinical trial updates from 2024 ASH annual meeting
Abstract Menin inhibitors, which target the KMT2A-menin protein-protein interaction to inhibit blasts proliferation and induce differentiation, have demonstrated potential effects on acute leukemia subtypes characterized by overexpression of HOXA gene cluster and MEIS1 (including KMT2A rearrangement...
| 出版年: | Journal of Hematology & Oncology |
|---|---|
| 主要な著者: | , , , |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
BMC
2025-06-01
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| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s13045-025-01718-x |