Overexpression of klotho suppresses growth and pulmonary metastasis of osteosarcoma in vivo

Abstract Klotho is originally discovered as an anti-aging gene and knock-out of klotho accelerates aging in mice. Subsequent studies support the anti-carcinogenesis role of klotho in a variety of human malignancies. The present study investigated the role of klotho on growth and metastasis of osteos...

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Bibliographic Details
Published in:Genetics and Molecular Biology
Main Authors: Ying Li, Hai-jun Xiao, Feng Xue
Format: Article
Language:English
Published: Sociedade Brasileira de Genética
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000400707&lng=en&tlng=en