Nucleophosmin mutation in Southeast Asian acute myeloid leukemia: eight novel variants, FLT3 coexistence and prognostic impact of NPM1/FLT3 mutations
NPM1 mutations were investigated in 400 Southeast Asian leukemia patients and were detectable in 105 cases (26.25%) of acute myeloid leukemia but in no cases of acute lymphoid leukemia or chronic myeloid leukemia. Eight novel and 5 known mutations were identified. All predicted novel proteins shared...
| Published in: | Haematologica |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2008-10-01
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| Online Access: | https://haematologica.org/article/view/5040 |