The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts

Background: Lipotoxicity causes endoplasmic reticulum (ER) stress, leading to cell apoptosis. Sirtuin 1 (Sirt1) regulates gene transcription and cellular metabolism. In this study, we investigated the role of Sirt1 in palmitate-induced ER stress. Methods: Both H9c2 myoblasts and heart-specific <i...

Full description

Bibliographic Details

Published in:	Life
Main Authors:	Hsiang-Yu Yang, Jhao-Ying Chen, Yen-Nien Huo, Pei-Ling Yu, Pei-Zhen Lin, Shih-Che Hsu, Shih-Ming Huang, Chien-Sung Tsai, Chih-Yuan Lin
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	palmitate endoplasmic reticulum stress sirtuin 1
Online Access:	https://www.mdpi.com/2075-1729/12/2/182