Molecular basis of F-actin regulation and sarcomere assembly via myotilin.

Sarcomeres, the basic contractile units of striated muscle cells, contain arrays of thin (actin) and thick (myosin) filaments that slide past each other during contraction. The Ig-like domain-containing protein myotilin provides structural integrity to Z-discs-the boundaries between adjacent sarcome...

Full description

Bibliographic Details

Published in:	PLoS Biology
Main Authors:	Julius Kostan, Miha Pavšič, Vid Puž, Thomas C Schwarz, Friedel Drepper, Sibylle Molt, Melissa Ann Graewert, Claudia Schreiner, Sara Sajko, Peter F M van der Ven, Adekunle Onipe, Dmitri I Svergun, Bettina Warscheid, Robert Konrat, Dieter O Fürst, Brigita Lenarčič, Kristina Djinović-Carugo
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2021-04-01
Online Access:	https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001148&type=printable