Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling

Abstract Background Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have emerged as a powerful tool for disease modeling, though their immature nature currently limits translation into clinical practice. Maturation strategies increasingly pay attention to cardiac metabolism because o...

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Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Sofija Vučković, Rafeeh Dinani, Edgar E. Nollet, Diederik W. D. Kuster, Jan Willem Buikema, Riekelt H. Houtkooper, Miranda Nabben, Jolanda van der Velden, Birgit Goversen
Format:	Article
Language:	English
Published:	BMC 2022-07-01
Subjects:	iPSC Stem cells Cardiomyocyte Metabolism Maturation HCM
Online Access:	https://doi.org/10.1186/s13287-022-03021-9