Gram-Negative Bacteria Salmonella typhimurium Boost Leukotriene Synthesis Induced by Chemoattractant fMLP to Stimulate Neutrophil Swarming

Leukotriene synthesis in neutrophils is critical for host survival during infection. In particular, leukotriene B4 (LTB4) is a powerful neutrophil chemoattractant that plays a crucial role in neutrophil swarming. In this work, we demonstrated that preincubation of human neutrophils with Salmonella t...

Full description

Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Ekaterina A. Golenkina, Svetlana I. Galkina, Olga Pletjushkina, Boris Chernyak, Tatjana V. Gaponova, Yulia M. Romanova, Galina F. Sud’ina
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-01-01
Subjects:	neutrophil bacteria Salmonella typhimurium intracellular calcium 5-lipoxygenase leukotriene B4 neutrophil swarming
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.814113/full