A double-edged sword role of IFN-γ-producing iNKT cells in sepsis: Persistent suppression of Treg cell formation in an Nr4a1-dependent manner

Summary: Sepsis, a leading cause of mortality in intensive care units worldwide, lacks effective treatments for advanced-stage sepsis. Therefore, understanding the underlying mechanisms of this disease is crucial. This study reveals that invariant natural killer T (iNKT) cells have an opposing role...

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書誌詳細

出版年:	iScience
主要な著者:	Yingyu Qin, Yilin Qian, Shengqiu Liu, Rong Chen
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2024-12-01
主題:	Biological sciences Immune response Immune system Immunology Natural sciences
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2589004224026890