Novel Isatin–Chalcone Hybrid Molecules: Design, Synthesis and Anti-Neuroinflammatory Activity Evaluation

Neuroinflammation is considered a significant factor in triggering numerous neurodegenerative diseases. Hence, the development of effective anti-inflammatory drugs is of utmost urgency. In this study, three series of new isatin–chalcone hybrid derivatives were successfully designed and synthesized,...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Rongrong Wang, Zhili Zhang, Wei Jiang, Junyi Liu, Chao Tian, Meng Wang
Format:	Article
Language:	English
Published:	MDPI AG 2025-03-01
Subjects:	anti-neuroinflammatory isatin nitric oxide TNF-α IL-6
Online Access:	https://www.mdpi.com/1420-3049/30/7/1421