The Interplay of Glycosaminoglycans and Cysteine Cathepsins in Mucopolysaccharidosis

Mucopolysaccharidosis (MPS) consists of a group of inherited lysosomal storage disorders that are caused by a defect of certain enzymes that participate in the metabolism of glycosaminoglycans (GAGs). The abnormal accumulation of GAGs leads to progressive dysfunctions in various tissues and organs d...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Alexis David, Thibault Chazeirat, Ahlame Saidi, Gilles Lalmanach, Fabien Lecaille
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Subjects:
cysteine proteases
glycosaminoglycans
inhibition
mucopolysaccharidosis
proteolysis
Online Access:https://www.mdpi.com/2227-9059/11/3/810

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https://www.mdpi.com/2227-9059/11/3/810

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