Cancer and lymphatic marker FOXC2 drives wound healing and fibrotic tissue formation

IntroductionThe FOXC2 transcription factor has been tied to a wide range of disease states, serving as a promising prognostic biomarker associated with aggressive basal-like human breast cancers (increased cancer invasion and metastasis). Dysregulation of FOXC2 expression has also been found to prom...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Maia B. Granoski, Katharina S. Fischer, William W. Hahn, Dharshan Sivaraj, Hudson C. Kussie, Filiberto Quintero, Abdelrahman M. Alsharif, Eamonn McKenna, Jonathan P. Yasmeh, Andrew C. Hostler, Maria Gracia Mora Pinos, Robert P. Erickson, Marlys H. Witte, Kellen Chen, Geoffrey C. Gurtner
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-10-01
Subjects:	FOXC2 lymphatics wound healing inflammation fibrosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2024.1427113/full