Novel Severe Hemophilia A Mouse Model with Factor VIII Intron 22 Inversion
Hemophilia A (HA) is an X-linked recessive blood coagulation disorder, and approximately 50% of severe HA patients are caused by <i>F8</i> intron 22 inversion (F8I22I). However, the F8I22I mouse model has not been developed despite being a necessary model to challenge pre-clinical study....
| Published in: | Biology |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-07-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-7737/10/8/704 |