Development of a Chicken Immunoglobulin Heavy Chain Variable Region (VH) Single-Domain Antibody (sdAb) Against Calsequestrin (CSQ) and Its Application

<b>Background/Objectives:</b> Calsequestrin (CSQ) is a calcium-binding protein that is highly soluble and can serve as a solubility-enhancing fusion tag in recombinant protein expression. Its unique property of calcium-induced precipitation followed by EDTA-mediated resolubilization enab...

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Bibliographic Details

Published in:	Antibodies
Main Authors:	Sun Lee, Seoryeong Park, Hyunji Yang, Geummi Cho, Seung Youn Lee, Donggeun Lee, Nara Tae, Dae Hee Kim, Junho Chung
Format:	Article
Language:	English
Published:	MDPI AG 2025-09-01
Subjects:	single-domain antibody chicken-derived VH antibody Calsequestrin phage display antibody engineering
Online Access:	https://www.mdpi.com/2073-4468/14/3/80