Detailed Kinematic Analysis Reveals Subtleties of Recovery from Contusion Injury in the Rat Model with DREADDs Afferent Neuromodulation

Spinal cord injury (SCI) often results in long-term locomotor impairments, and strategies to enhance functional recovery remain limited. While epidural electrical stimulation (EES) has shown clinical promise, our understanding of the mechanisms by which it improves function remains incomplete. Here,...

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Bibliographic Details

Published in:	Bioengineering
Main Authors:	Gavin Thomas Koma, Kathleen M. Keefe, George Moukarzel, Hannah Sobotka-Briner, Bradley C. Rauscher, Julia Capaldi, Jie Chen, Thomas J. Campion, Jacquelynn Rajavong, Kaitlyn Rauscher, Benjamin D. Robertson, George M. Smith, Andrew J. Spence
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	DREADDs or chemogenetics designer receptors exclusively activated by designer drugs clozapine-N-oxide (CNO) functional recovery after SCI kinematics plasticity
Online Access:	https://www.mdpi.com/2306-5354/12/10/1080