AC099850.3 promotes HBV-HCC cell proliferation and invasion through regulating CD276: a novel strategy for sorafenib and immune checkpoint combination therapy

Abstract Background This study investigates the molecular mechanisms of CC@AC&SF@PP NPs loaded with AC099850.3 siRNA and sorafenib (SF) for improving hepatitis B virus-related hepatocellular carcinoma (HBV-HCC). Methods A dataset of 44 HBV-HCC patients and their survival information was selected...

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Bibliographic Details

Published in:	Journal of Translational Medicine
Main Authors:	Aoxiao He, Zhihao Huang, Qian Feng, Shan Zhang, Fan Li, Dan Li, Hongcheng Lu, Jiakun Wang
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Hepatitis B virus-related hepatocellular carcinoma AC099850.3 CD276 Cell cycle Cell proliferation and invasion Nanoparticles
Online Access:	https://doi.org/10.1186/s12967-024-05576-y