Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain

Glutamate is present in the brain at an average concentration—typically 10–12 mM—far in excess of those of other amino acids. In glutamate-containing vesicles in the brain, the concentration of glutamate may even exceed 100 mM. Yet because glutamate is a major excitatory neurotransmitter, the concen...

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書誌詳細

出版年:	Biomolecules
主要な著者:	Arthur J. L. Cooper, Thomas M. Jeitner
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2016-03-01
主題:	Amino acids ammonia aspartate aspartate aminotransferase glutamate glutaminase glutamate dehydrogenase glutamine glutamine synthetase α-ketoglutarate
オンライン･アクセス:	http://www.mdpi.com/2218-273X/6/2/16