Adaptive immune changes associate with clinical progression of Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) is the most frequent cause of dementia. Recent evidence suggests the involvement of peripheral immune cells in the disease, but the underlying mechanisms remain unclear. Methods We comprehensively mapped peripheral immune changes in AD patients with mild...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Molecular Neurodegeneration
المؤلفون الرئيسيون:	Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodriguez, Inge M. W. Verberk, Sanne G. S. Verberk, Danielle W. R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff, Dorine Wouters, Jan Van den Bossche, Juan J. Garcia-Vallejo, Afina W. Lemstra, Maarten E. Witte, Wiesje M. van der Flier, Charlotte E. Teunissen, Helga E. de Vries
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2024-04-01
الموضوعات:	Alzheimer’s disease T cells TEMRA cells Adaptive immunity APOE Neuroinflammation
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13024-024-00726-8