Early timepoint 99mTc-DPD whole body scintigraphy and quantitative SPECT/CT imaging for diagnosis of cardiac ATTR amyloidosis

Abstract Background Cardiac transthyretin amyloidosis (ATTR-CM) is a progressive myocardial disease ultimately leading to heart failure. Standard diagnostic workup includes 99mTc-DPD scintigraphy performed after 2.5–3 h. The purpose of this study is to compare early (1 h after injection) to late ima...

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Bibliographic Details

Published in:	EJNMMI Research
Main Authors:	Stephan Settelmeier, Lukas Kessler, Noah Hammersen, Maria Papathanasiou, Christoph Rischpler, Alexander Carpinteiro, Sara Oubari, Lars Michel, Julia Vogel, Tim Wollenweber, Jing Ning, Marcus Hacker, Clemens P. Spielvogel, Zohreh Varasteh, Wolfgang P. Fendler, Francesco Barbato, Pedro Fragoso Costa, Stephan Leyser, Tienush Rassaf, Ken Herrmann, Tugce Telli, David Kersting
Format:	Article
Language:	English
Published:	SpringerOpen 2026-06-01
Subjects:	Cardiac amyloidosis ATTR DPD-SPECT Nuclear cardiology Perugini score
Online Access:	https://doi.org/10.1186/s13550-026-01466-0