Gut microbiome influences efficacy of Endostatin combined with PD-1 blockade against colorectal cancer

Abstract The combination of anti-angiogenic drugs and immune checkpoint inhibitors (ICIs) in the treatment of tumors is emerging as a way to improve ICIs-resistant tumor therapy. In addition, gut microbes (GMs) are involved in angiogenesis in the tumor microenvironment and are also associated with t...

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Bibliographic Details

Published in:	Molecular Biomedicine
Main Authors:	Jie Xu, Yaomei Tian, Binyan Zhao, Die Hu, Siwen Wu, Jing ma, Li Yang
Format:	Article
Language:	English
Published:	Springer 2024-09-01
Subjects:	Gut microbes Anti-angiogenic therapy Adenovirus encoding human endostatin PD-1 blockade Cancer therapy
Online Access:	https://doi.org/10.1186/s43556-024-00200-3