miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma

MicroRNAs are a group of endogenous small non-coding RNAs commonly dysregulated in tumorigenesis, including glioblastoma (GBM), the most malignant brain tumor with rapid proliferation, diffuse invasion, and therapeutic resistance. Accumulating evidence has manifested that miR-1258 exerts an inhibito...

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發表在:	Frontiers in Oncology
Main Authors:	Hongkun Qin, Yanping Gui, Rong Ma, Heng Zhang, Yabing Guo, Yuting Ye, Jia Li, Li Zhao, Yajing Wang
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2021-05-01
主題:	miR-1258 glioblastoma E2F1 temozolomide transcriptional regulation tumorigenesis
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fonc.2021.671144/full