Landscape of histone modifications in a sponge reveals the origin of animal cis-regulatory complexity

Combinatorial patterns of histone modifications regulate developmental and cell type-specific gene expression and underpin animal complexity, but it is unclear when this regulatory system evolved. By analysing histone modifications in a morphologically-simple, early branching animal, the sponge Amph...

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Bibliographic Details

Published in:	eLife
Main Authors:	Federico Gaiti, Katia Jindrich, Selene L Fernandez-Valverde, Kathrein E Roper, Bernard M Degnan, Miloš Tanurdžić
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2017-04-01
Subjects:	A. queenslandica evolution of multicellularity histone modifications cis-regulation enhancers gene expression
Online Access:	https://elifesciences.org/articles/22194