GraS signaling in Staphylococcus aureus is regulated by a single D35 residue in the extracellular loop

ABSTRACT Bacterial two-component systems are crucial features of bacterial pathogens such as methicillin-resistant Staphylococcus aureus to overcome environmental and antimicrobial stresses by activating regulons to interfere with the bactericidal mechanisms. GraRS is a unique subset of two-componen...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Junho Cho, Adhar C. Manna, Helah S. Snelling, Ambrose L. Cheung
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-10-01
Subjects:	MRSA two-component regulatory systems antimicrobial peptides GraRS TCS
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.01982-23