Ghrelin receptor antagonist JMV2959 blunts cocaine and oxycodone drug-seeking, but not self-administration, in male rats

The drug overdose crisis has spawned serious health consequences, including the increased incidence of substance use disorders (SUDs), conditions manifested by escalating medical and psychological impairments. While medication management is a key adjunct in SUD treatment, this crisis has crystallize...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Christina R. Merritt, Erik J. Garcia, Victoria D. Brehm, Robert G. Fox, F. Gerard Moeller, Noelle C. Anastasio, Kathryn A. Cunningham
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-09-01
Subjects:	cocaine oxycodone growth hormone secretagogue receptor 1α (GHS1αR) Sprague-Dawley rat self-administration cue-reinforced drug seeking
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1268366/full