Magnesium-enriched deep-sea water inhibits NLRP3 inflammasome activation and dampens inflammation

The NLRP3 inflammasome is an essential component of the innate immune system, but excessive activation can lead to inflammatory diseases. Ion fluxes across the plasma membrane or from intracellular stores are known to regulate NLRP3 inflammasome activation. Deep-sea water (DSW) contains high concent...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Hsueh-Hsiao Wang, Chi-Ruei Huang, Hsin-Chung Lin, Hsin-An Lin, Yu-Jen Chen, Kuen-Jou Tsai, Chieh-Tien Shih, Kuo-Yang Huang, David M. Ojcius, Ming-Hang Tsai, Kuang-Wen Tseng, Lih-Chyang Chen
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	Deep-sea water Macrophages Magnesium NLRP3 inflammasome
Online Access:	http://www.sciencedirect.com/science/article/pii/S240584402411167X