Real-time evaluation of signal accuracy in wastewater surveillance of pathogens with high rates of mutation

Abstract Wastewater surveillance of coronavirus disease 2019 (COVID-19) commonly applies reverse transcription-quantitative polymerase chain reaction (RT-qPCR) to quantify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentrations in wastewater over time. In most applications wo...

Full description

Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Ocean Thakali, Élisabeth Mercier, Walaa Eid, Martin Wellman, Julia Brasset-Gorny, Alyssa K. Overton, Jennifer J. Knapp, Douglas Manuel, Trevor C. Charles, Lawrence Goodridge, Eric J. Arts, Art F. Y. Poon, R. Stephen Brown, Tyson E. Graber, Robert Delatolla, Christopher T. DeGroot, Ontario Wastewater Surveillance Consortium
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-02-01
Online Access:	https://doi.org/10.1038/s41598-024-54319-y