Brain Aging and APOE ε4 Interact to Reveal Potential Neuronal Compensation in Healthy Older Adults

Compensation implies the recruitment of additional neuronal resources to prevent the detrimental effect of age-related neuronal decline on cognition. Recently suggested statistical models comprise behavioral performance, brain activation, and measures related to aging- or disease-specific pathologic...

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Bibliographic Details

Published in:	Frontiers in Aging Neuroscience
Main Authors:	Elisa Scheller, Lena V. Schumacher, Jessica Peter, Jacob Lahr, Julius Wehrle, Christoph P. Kaller, Christian Gaser, Stefan Klöppel
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-03-01
Subjects:	functional magnetic resonance imaging BrainAGE aging APOE neuronal compensation working memory
Online Access:	http://journal.frontiersin.org/article/10.3389/fnagi.2018.00074/full