Different cell compositions and a novel somatic KCNJ5 variant found in a patient with bilateral adrenocortical adenomas secreting aldosterone and cortisol

IntroductionThis study aimed to explore the possible pathogenesis of a rare case of co-existing Cushing’s syndrome (CS) and primary aldosteronism (PA) caused by bilateral adrenocortical adenomas secreting aldosterone and cortisol, respectively.MethodsA 41-year-old Chinese woman with severe hypertens...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Liling Zhao, Jinjing Wan, Yujun Wang, Wenjun Yang, Qi Liang, Jinrong Wang, Ping Jin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	primary aldosteronism Cushing’s syndrome KCNJ5 gene adrenal vein sampling CYP11B1 CYP11B2
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1068335/full