Modified comet assay with Giemsa staining: a suitable method for assessing genotoxicity in rats

ABSTRACT The present study tested a comet assay that was modified for compatibility with Giemsa staining to assess the drug genotoxicity in the peripheral blood of rats. We analysed the peripheral blood of 16 female Wistar rats (N=8 rats/group) from a control group and from a group that was treated...

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Bibliographic Details

Published in:	Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Main Authors:	M.A.B. Fagiani, A. Fluminhan, E. Araújo, L.S.L.S. Reis
Format:	Article
Language:	English
Published:	Universidade Federal de Minas Gerais 2020-07-01
Subjects:	comet assay azure stains mutagenicity tests genetics electrophoresis
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352020000300853&tlng=en