Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury

Peripheral nerve regeneration relies on the ability of Schwann cells to support the regrowth of damaged axons. Schwann cells re-differentiate when reestablishing contact with the sprouting axons, with large fibers becoming remyelinated and small nociceptive fibers ensheathed and collected into Remak...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Maj Ulrichsen, Nádia P. Gonçalves, Simin Mohseni, Simone Hjæresen, Thomas L. Lisle, Simon Molgaard, Niels K. Madsen, Olav M. Andersen, Åsa F. Svenningsen, Simon Glerup, Anders Nykjær, Christian B. Vægter
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Subjects:	nerve injury NT-3 TrkC sortilin Schwann cell Remak bundle
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2022.856734/full