Effective synthesis of circRNA via a thermostable T7 RNA polymerase variant as the catalyst

Introduction:Circular RNAs (circRNAs) are endogenous noncoding RNAs (ncRNAs) with transcriptional lengths ranging from hundreds to thousands. circRNAs have attracted attention owing to their stable structure and ability to treat complicated diseases. Our objective was to create a one-step reaction f...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Bioengineering and Biotechnology
المؤلفون الرئيسيون: Wei He, Xinya Zhang, Yangxiaoyu Zou, Ji Li, Le Chang, Yu-Cai He, Qiuheng Jin, Jianren Ye
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2024-04-01
الموضوعات:
circRNA
transcription
thermostability
mutations
cyclization
synthesis
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1356354/full

الانترنت

https://www.frontiersin.org/articles/10.3389/fbioe.2024.1356354/full

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