MHC class I trafficking signal improves induction of cytotoxic T lymphocyte using artificial antigen presenting cells

Inducing antigen peptide-specific cytotoxic T cells is challenging, partly due to the difficulty of maintaining the quality of antigen-presenting cells, such as dendritic cells. Consequently, artificial antigen-presenting cells (aAPCs) derived from the erythroleukemia cell line K562 have been employ...

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Bibliographic Details

Published in:	Biochemistry and Biophysics Reports
Main Authors:	Kenta Sasaki, Kenji Murata, Tomoyuki Minowa, Naoki Shijubou, Hiroki Kobayashi, Munehide Nakatsugawa, Aiko Murai, Yuka Mizue, Terufumi Kubo, Takayuki Kanaseki, Tomohide Tsukahara, Hisashi Uhara, Akemi Ishida-Yamamoto, Yoshihiko Hirohashi, Toshihiko Torigoe
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	Artificial antigen-presenting cells (aAPC) Erythroleukemia cell line K562 MHC class I trafficking signal (MITD)
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405580825000330