Kynurenine in IDO1high cancer cell-derived extracellular vesicles promotes angiogenesis by inducing endothelial mitophagy in ovarian cancer

Abstract Background Mitophagy, a prominent cellular homeostasis process, has been implicated in modulating endothelial cell function. Emerging evidence suggests that extracellular vesicles (EVs) participate in intercellular communication, which could modulate tumor angiogenesis, a hallmark of ovaria...

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Bibliographic Details

Published in:	Journal of Translational Medicine
Main Authors:	Xiang Ying, Xiaocui Zheng, Xiaoqian Zhang, Yujia Yin, Xipeng Wang
Format:	Article
Language:	English
Published:	BMC 2024-03-01
Subjects:	IDO1 Extracellular vesicles Mitophagy Angiogenesis Ovarian cancer
Online Access:	https://doi.org/10.1186/s12967-024-05054-5