A Cationic Tetraphenylethene as a Light-Up Supramolecular Probe for DNA G-Quadruplexes

Guanine-quadruplexes (G4s) are targets for anticancer therapeutics. In this context, human telomeric DNA (HT-DNA) that can fold into G4s sequences are of particular interest, and their stabilization with small molecules through a visualizable process has become a challenge. As a new type of ligand f...

Full description

Bibliographic Details

Published in:	Frontiers in Chemistry
Main Authors:	Clément Kotras, Mathieu Fossépré, Maxime Roger, Virginie Gervais, Sébastien Richeter, Philippe Gerbier, Sébastien Ulrich, Mathieu Surin, Sébastien Clément
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-07-01
Subjects:	tetraphenylethene G-quadruplexes fluorescence light-up probe supramolecular
Online Access:	https://www.frontiersin.org/article/10.3389/fchem.2019.00493/full