Effect of Shikonin on Spinal Cord Injury in Rats Via Regulation of HMGB1/TLR4/NF-kB Signaling Pathway

Background/Aims: Shikonin, a compound extracted from Zicao, has been demonstrated to hold anti-bacterial, anti-inflammatory, and anti-tumor activities in various diseases and it has been shown to protect human organs from injuries. However, the effect of shikonin on the recovery of spinal cord injur...

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Bibliographic Details

Published in:	Cellular Physiology and Biochemistry
Main Authors:	Yihui Bi, Yapeng Zhu, Mingkai Zhang, Keke Zhang, Xingyi Hua, Zheng Fang, Jian Zhou, Wenjie Dai, Yixing Cui, Jun Li, Tao You
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2017-09-01
Subjects:	Shikonin SCI Inflammation response Apoptosis HMGB1/TLR4/NF-κB signaling pathway
Online Access:	http://www.karger.com/Article/FullText/480474