Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and culture.

The stresses encountered during islet isolation and culture may have deleterious effects on beta-cell physiology. However, the biological response of human islet cells to isolation remains poorly characterized. A better understanding of the network of signaling pathways induced by islet isolation an...

詳細記述

書誌詳細

出版年:	PLoS ONE
主要な著者:	Sarita Negi, Arif Jetha, Reid Aikin, Craig Hasilo, Rob Sladek, Steven Paraskevas
フォーマット:	論文
言語:	英語
出版事項:	Public Library of Science (PLoS) 2012-01-01
オンライン･アクセス:	http://europepmc.org/articles/PMC3267725?pdf=render