RHO-Associated Coiled-Coil-Containing Protein Kinase Inhibitors Significantly Modulate the Epithelial–Mesenchymal Transition Induced by TGF-β2 in the 2-D and 3-D Cultures of Human Corneal Stroma Fibroblasts

Background/Objectives: The objective of the present study was to examine the unidentified effects that RHO-associated coiled-coil-containing protein kinase 1 and 2 antagonists exert on the transforming growth factor beta2-induced epithelial–mesenchymal transition of the human corneal stroma. Methods...

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出版年:	Biomedicines
主要な著者:	Araya Umetsu, Yosuke Ida, Tatsuya Sato, Megumi Higashide, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2024-12-01
主題:	three-dimensional spheroid culture TGF-β2 human corneal stroma fibroblasts (HCSFs) corneal injury model ROCK inhibitor
オンライン･アクセス:	https://www.mdpi.com/2227-9059/12/12/2784