Vaccination with immune complexes modulates the elicitation of functional antibodies against HIV-1

IntroductionNeutralizing antibodies (Abs) are one of the immune components required to protect against viral infections. However, developing vaccines capable of eliciting neutralizing Abs effective against a broad array of HIV-1 isolates has been an arduous challenge.ObjectiveThis study sought to te...

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الحاوية / القاعدة:	Frontiers in Immunology
المؤلفون الرئيسيون:	Catarina E. Hioe, Xiaomei Liu, Andrew N. Banin, Daniel W. Heindel, Jéromine Klingler, Priyanka G. Rao, Christina C. Luo, Xunqing Jiang, Shilpi Pandey, Tracy Ordonez, Philip Barnette, Maxim Totrov, Jiang Zhu, Arthur Nádas, Susan Zolla-Pazner, Chitra Upadhyay, Xiaoying Shen, Xiang-Peng Kong, Ann J. Hessell
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2023-10-01
الموضوعات:	HIV-1 vaccine HIV-1 Env antibody immune complex (IC) virus neutralization ADCP
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1271686/full