Exploring the interplay of MTHFR and FGG polymorphisms with serum levels of adiponectin and leptin in pediatric lupus nephritis: a pilot study

Abstract Background Adiponectin and leptin are pivotal in the regulation of metabolism. Pediatric lupus nephritis (pLN), a manifestation of childhood systemic lupus erythematosus (SLE) affecting the kidneys, is associated with impaired adipokine levels, suggesting a role in pLN pathogenesis. The aim...

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Bibliographic Details

Published in:	Egyptian Journal of Medical Human Genetics
Main Authors:	Gloria Garavito De Egea, Alex Domínguez-Vargas, Luis Fang, Nicole Pereira-Sanandrés, Jonathan Rodríguez, Gustavo Aroca-Martinez, Zilac Espítatela, Clara Malagón, Antonio Iglesias-Gamarra, Ana Moreno-Woo, Guillermo López-Lluch, Eduardo Egea
Format:	Article
Language:	English
Published:	SpringerOpen 2024-03-01
Subjects:	Pediatric lupus nephritis Adiponectin Leptin MTHFR FGG Polymorphism
Online Access:	https://doi.org/10.1186/s43042-024-00507-4