Long noncoding RNA CASC11 suppresses sorafenib-triggered ferroptosis via stabilizing SLC7A11 mRNA in hepatocellular carcinoma cells

Abstract As a frontline treatment for patients with advanced hepatocellular carcinoma (HCC), sorafenib is an effective drug approved by the Food and Drug Administration (FDA). Ferroptosis, a newly defined programmed cell death process with the hallmark of the accumulation of iron-dependent lipid per...

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Bibliographic Details
Published in:Discover Oncology
Main Authors: Fei Chen, Liang Wang
Format: Article
Language:English
Published: Springer 2023-08-01
Subjects:
SLC7A11
mRNA stability
Sorafenib
Ferroptosis
Online Access:https://doi.org/10.1007/s12672-023-00761-9

Internet

https://doi.org/10.1007/s12672-023-00761-9

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