NSC 18725, a Pyrazole Derivative Inhibits Growth of Intracellular Mycobacterium tuberculosis by Induction of Autophagy

The increasing incident rates of drug-resistant tuberculosis (DR-TB) is a global health concern and has been further complicated by the emergence of extensive and total drug-resistant strains. Identification of new chemical entities which are compatible with first-line TB drugs, possess activity aga...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Garima Arora, Gagandeep, Assirbad Behura, Tannu Priya Gosain, Ravi P. Shaliwal, Saqib Kidwai, Padam Singh, Shamseer Kulangara Kandi, Rohan Dhiman, Diwan S. Rawat, Ramandeep Singh
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-01-01
Subjects:	Mycobacterium tuberculosis phenotypic screening pyrazole scaffold NSC-18725 autophagy
Online Access:	https://www.frontiersin.org/article/10.3389/fmicb.2019.03051/full