Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene

Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma is characterized by 2p23/ALK aberrations, including the classic t(2;5)(p23;q35)/NPM1-ALK rearrangement present in ~80% of cases and several variant t(2p23/ALK) occurring in the remaining cases. The ALK fusion partners play a ke...

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Bibliographic Details

Published in:	Haematologica
Main Authors:	Jo-Anne van der Krogt, Marlies Vanden Bempt, Julio Finalet Ferreiro, Nicole Mentens, Kris Jacobs, Ursula Pluys, Kathleen Doms, Ellen Geerdens, Anne Uyttebroeck, Pascal Pierre, Lucienne Michaux, Timothy Devos, Peter Vandenberghe, Thomas Tousseyn, Jan Cools, Iwona Wlodarska
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2017-09-01
Online Access:	https://haematologica.org/article/view/8196