High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

Microtubule-based transport by the kinesin motors, powered by ATP hydrolysis, is essential for a wide range of vital processes in eukaryotes. We obtained insight into this process by developing atomic models for no-nucleotide and ATP states of the monomeric kinesin motor domain on microtubules from...

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Bibliographic Details
Published in:eLife
Main Authors: Zhiguo Shang, Kaifeng Zhou, Chen Xu, Roseann Csencsits, Jared C Cochran, Charles V Sindelar
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-11-01
Subjects:
Online Access:https://elifesciences.org/articles/04686