Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition

Objectives. Hypoxia-inducible factor 1α (HIF1α) and Tet methylcytosine dioxygenase 2 (TET2) have been reported to mediate nasal polypogenesis through the epithelial-to-mesenchymal transition (EMT). Additionally, HIF1α can regulate the expression and function of TET2. However, the precise mechanism o...

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Bibliographic Details

Published in:	Clinical and Experimental Otorhinolaryngology
Main Authors:	Kunyu Liu, Yu Xu
Format:	Article
Language:	English
Published:	Korean Society of Otorhinolaryngology-Head and Neck Surgery 2024-02-01
Subjects:	sinusitis nasal polyp tet2, hif1α epithelial-mesenchymal transition
Online Access:	http://www.e-ceo.org/upload/pdf/ceo-2023-01340.pdf