CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer.

The CBFB gene is frequently mutated in several types of solid tumors. Emerging evidence suggests that CBFB is a tumor suppressor in breast cancer. However, our understanding of the tumor suppressive function of CBFB remains incomplete. Here, we analyze genetic interactions between mutations of CBFB...

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發表在:	PLoS Genetics
Main Authors:	Navdeep Malik, Hualong Yan, Howard H Yang, Gamze Ayaz, Wendy DuBois, Yu-Chou Tseng, Young-Im Kim, Shunlin Jiang, Chengyu Liu, Maxwell Lee, Jing Huang
格式:	Article
語言:	英语
出版:	Public Library of Science (PLoS) 2021-05-01
在線閱讀:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009553&type=printable