Effect of Acute Lung Injury (ALI) Induced by Lipopolysaccharide (LPS) on the Pulmonary Pharmacokinetics of an Antibody

Objective: To investigate the effect of Lipopolysaccharide (LPS)-induced acute lung injury (ALI) on the pulmonary pharmacokinetics (PK) of a systemically administered antibody in mice. Method: The PK of a non-target-binding antibody was evaluated in healthy mice and mice with intratracheal instillat...

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Bibliographic Details
Published in:Antibodies
Main Authors: Shweta Jogi, Dhaval K. Shah
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Subjects:
antibody
pulmonary
lung
pharmacokinetics
ALI
LPS
Online Access:https://www.mdpi.com/2073-4468/14/2/33

Internet

https://www.mdpi.com/2073-4468/14/2/33

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